The effect of your variant on RNA or protein operate, based upon experimental evidence from submitters.
This benefit is calculated by NCBI determined by knowledge from submitters. Study our guidelines for calculating the review standing. The number of submissions which lead to this assessment status is demonstrated in parentheses.
This date represents the last time this VCV file was current. The update could be due to an update to one of many involved submitted documents (SCVs), or due to an update that ClinVar created on the variant for instance incorporating HGVS expressions or simply a rs selection.
The global insignificant allele frequency calculated via the a thousand Genomes Task. The small allele at this place is indicated in parentheses and could be unique with the allele represented by this VCV file.
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There are no citations for germline classification of the variant in ClinVar. If you know of citations for this variation, please take into thr777 consideration submitting that information to ClinVar.
The number of variants in ClinVar that are contained inside of this gene, with a backlink to watch the list of variants.
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Stars characterize the mixture evaluation position, or the level of evaluation supporting the combination germline classification for this VCV file.
The volume of variants in ClinVar for this gene, like smaller variants in the gene and bigger CNVs that overlap or entirely contain the gene.
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